By unraveling the secrets underlying fundamental biological processes, we can find innovative approaches to diagnose, treat, and prevent disease.
150
Ongoing research projects
$1.8B
Spent on research to date
500
Members
60
Predoctoral researchers
Molecular and Cell Biology
We seek to understand how genes are regulated at the post-transcriptional level during vertebrate development and in human disease, and to uncover the mechanisms underlying the translation and stability of messenger RNA.
Genetics and Genomics
We seek to understand how genome instability impacts cells, tissues, and organisms during development, female reproductive aging, and cancer.
Development and Regeneration
Our mission is to understand the cellular and molecular mechanisms underlying development, evolution, and regeneration.
Molecular and Cell Biology
We seek to understand aging, the inexorable decline in cellular and bodily function that results from the unidirectional nature of self-assembly by supersaturated proteins.
Genetics and Genomics
Our lab is passionate about understanding all aspects of meiosis, the specialized cell division of sexually reproductive species.
Molecular and Cell Biology
We seek to uncover how changes in ribosome composition impact protein production and contribute to complex physiological processes, including development, adaptation, and disease initiation and progression.
Development and Regeneration
We seek to understand the genetic and regulatory bases underlying body plan formation during development and how different species evolve.
Development and Regeneration
We seek to understand the regulation of stem cells within blood-forming and intestinal systems and how this relates to cancer in humans.
Genetics and Genomics
Our lab seeks to uncover the molecular underpinnings of bacterial collective behaviors, focusing on space- and time-distinctive cell death.
Neuroscience
Our research integrates developmental neurobiology with systems biology and gene regulation with the goal of understanding brain wiring.
Development and Regeneration
The primary focus of our lab is understanding the development and regeneration of the zebrafish lateral line and the potential applications for promoting mammalian hair cell regeneration to restore hearing loss or deafness.
Evolutionary Biology
We seek to understand how animals adapt to extreme environments, resulting in unique genetic adaptations that may shed light on human metabolic conditions like diabetes and heart disease.
Development and Regeneration
Our lab seeks to uncover the cellular and genetic mechanisms responsible for regeneration and development.
Biochemistry
We seek to uncover the mechanisms of action of host-secreted peptides that provide important clues to decipher the fundamental biology of host-microbe interactions.
Development and Regeneration
Our focus is on decoding the gene regulatory networks involved in cell function of the neural crest, heart, and nervous system to uncover the mechanisms underpinning inflammation and regeneration and how they have evolved.
Neuroscience
Our lab investigates how distinct experiences in time may result in lasting behavioral changes. |
Development and Regeneration
Our focus is on how disruptions in ribosome formation and RNA transcription result in the death of neural crest cells that give rise to development of the head, face, and digestive tract.
Molecular and Cell Biology
Our research focuses on how DNA and proteins interact to regulate gene expression.
Neuroscience
We seek to uncover how neurons in the brain are associated with sensation and behavior, primarily in how we respond to odors and pheromones.
Genetics and Genomics
We are interested in understanding sexual reproduction and how its evolution is shaped by genetic parasites.
Genetics and Genomics
We seek to understand how different stretches of DNA provide information for gene transcription, expression, and regulation by developing computational tools for analyzing vast quantities of genetic information.
The unique collaboration between scientists in our labs and Technology Centers enables cutting-edge, solution-driven research to unravel the secrets of life.
