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20 November 2024
Postdoc Profile: Leo Yan
Q&A with Kostova Lab Postdoc Leo Yan
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Q&A with Stowers Postdoc Charles McAnany: "You must always start with a question; everything else flows from that."
What is your current research focus and why?
I want to understand the language of DNA. Ultimately, everything in an organism is determined by its DNA sequence, but we know very little about how the 'words' in DNA are interpreted by cellular machinery. I'm discovering which 'words' in the DNA are read out by the cell in order to determine how the DNA should be packaged in the nucleus.
Growing up, what career did you want to pursue?
I was sure I would be a chemical engineer. My dad was a mechanical engineer, and I loved making messes in the kitchen. After one week as a chemical engineer in college, I decided I didn't want to specify pumps for a living, and so I became a chemist.
When and how did you become interested in a career in science?
In ninth grade biology, we did an experiment where we burned steel wool, and measured how much heavier it got. When I saw the conservation of mass in action like that, I was hooked.
What made you decide to join the Zeitlinger lab at the Stowers Institute?
I had finished my Ph.D. studying molecular dynamics of protein-nucleic acid complexes, and Julia had an opening for a postdoc to study the dynamics of the early steps of DNA transcription. On top of that, this job also mixed in one of my other hobbies: machine learning. How could I not apply?
What is your favorite non-research related memory at the Stowers Institute so far?
The Stowers Creative Club has given me lots of opportunities to explore my scientific work from an artistic perspective. The stimulating discussions and very cool artwork are always a highlight of my month.
What is your favorite thing to do in Kansas City?
Being an amateur photographer, I love any opportunity to haul out my large-format camera and take some photos.
Where do you see yourself in 10 years?
I'd like to be teaching chemistry and computer science at a primarily undergraduate university.
What advice do you have for other people curious about a career in science?
You must always start with a question; everything else flows from that.
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16 November 2024
Until now, scientists didn’t fully understand how Chd7, a gene that helps unpack tightly wrapped DNA, becomes activated within the neural crest during development.
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07 November 2024
"It excites me to know that, as a team, we can accomplish things that few people in the world can do, and the Institute enables us to do that by providing all the necessary resources."
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01 November 2024
Organized by Stowers Institute Investigators Matt Gibson, Ph.D., Tatjana Sauka-Spengler, Ph.D., and Robb Krumlauf, Ph.D., the conference facilitated a collaborative environment aimed at creative scientific exchange. More than 100 participants attended, including 20 distinguished speakers and trainees.
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